I often wondered what the clay was, and it was only much later that I realized that it was Multani mitti
They include eloralintide, a peptide that mimics a hormone called amylin, and retatrutide, a once-weekly injectable that targets three receptors at once: glucose-dependent insulinotropic polypeptide (GIP), GLP-1, and glucagon.
For example, the amount of liver fat is strongly associated with cardiovascular disease, cancer, and many extrahepatic diseases 48
The compounds bind to entirely different receptors (beta-3 adrenergic vs GLP-1/GIP)
A 36 mg dose of the drug, taken once per day without food and water restrictions, reduced weight by an average of 12.4%, compared to 0.9% for participants in the placebo group