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Most GLP-1 medications target one receptor
At the currently approved maximum dose of 14mg, the PIONEER clinical trials showed weight loss of approximately 4-5kg (about 4-5% of body weight) over 26 weeks in patients with type 2 diabetes
Figure 2 The Cochrane Collaboration tool (Supplementary Table S3) was applied to assess risk of bias in all included studies
It comes down to what you are willing to tolerate for the outcomes you need
As mentioned, CJC-1295 no DAC has not been researched in humans and there is no information on potential dosing
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