GLP1/E improves metabolic and gonadal traits in a PCOS model of ovarian dysfunction We next assessed the metabolic, gonadal, and hormonal effects of the intervention with equivalent doses (10 nmol/kg) of GLP1, E, or GLP1/E in PNA mice, which retain ovulatory capacity albeit with clear dysregulation of ovarian cyclicity
These drugs mimic the gut hormone glucagon-like peptide-1 and are widely prescribed for weight reduction and glucose control (1 Trusted Source GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases Go to source)
Immunohorizons 6 , 476487 (2022)
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