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Plasma insulin levels remained constant in lean subjects but rose significantly in obese subjects after termination of the peptide infusions

These findings were correlated with levels of Von Willebrand Factor (VWF) or ADAMTS13 activity, involved in arterial thrombotic pathologies (26)

One metabolite that contributes substantially to atherosclerosis and can be used to estimate cardiovascular risk is trimethylamine-N-oxide (TMAO) (164)

The oxidative inactivation of human alpha-1 proteinase inhibitor

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