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Its harder to tease out because the data is a little noisier, but it appears the glucose reduction was also not quite at a plateau, suggesting further improvements may be forthcoming in longer term trials, especially if other anti-diabetic medications are on board
Its not just psychologicalits physiological
Compounded semaglutide, which is available through the Hers platform, contains the same active ingredient as the brand-name medications (but it hasn't been approved by the FDA)
Its not about willpower
Within the context of concurrent GLP-1R and GIPR agonism, however, preclinical energy-expenditure models suggest that GCGR engagement may contribute to resting metabolic rate modulation and fatty-acid oxidation in hepatic cell lines
