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Further, the CVOTs in general also suggested a potential benefit of GLP-1 RAs on HF, positioning GLP-1 RAs as another advanced option alongside SGLT2 inhibitors in the otherwise sparse treatment armamentarium for especially HFpEF

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If a woman shows signs of increasing proteinuria, hypertension, and deteriorating kidney function early in pregnancy, especially if she has a history of lupus nephritis, this strongly indicates the likelihood of a lupus nephritis flare-up (84, 94)