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In the event DSIP does ultimately undergo clinical development, intranasal administration can ensure a higher degree of patient compliance by eliminating side effects and discomfort commonly associated with peptide injections

iris.who.int/bitstream/handle/10665/43190/9241593024_eng.pdf (2005)

doi: 10.1021/jf050384i 101 CerdBLlorachRCernJJEspnJCToms-BarbernFA

These changes result in reduced intratesticular testosterone concentrations, testicular atrophy, and impaired spermatogenesis (77)