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Cognitive Behavioral Therapy and FDA-approved medications may be more suitable, at present, for individuals trying to reduce or stop substance use

doi: 10.1139/bcb-2021-0365 43 BudakMachnikGBudakRJabuzekKBodysABelowskiDet al

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Key Takeaways Side effects are predictable, dose-dependent, and time-limited for most patients Nausea typically peaks within 48 weeks and improves with body adaptation Each dose escalation produces a temporary, milder return of symptoms Weeks 26 are when most patients quit this is the wrong time to stop Protein, hydration, and resistance training prevent the most common long-term issues (muscle loss, fatigue, constipation) Serious side effects are uncommon but recognisable knowing the warning signs matters If symptoms are unmanageable, ask your prescriber to delay (not skip) a dose escalation References Hawkins-Jarrett ZC, PharmD

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