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Vaccination with rEE2 and rMCP antigens induces memory recall responses The first vaccinated elephant (A) received 20% of the eventual viral dose of MVA and half of the g protein boost dose during the first rMVA-EE2-MCP prime and protein boost cycle to initially assess safety and determine the dose range, which was then increased in the second prime-boost cycle to the final dose used in the rest of the trial
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An ideal acid cleavable linker antibody should remain intact during circulation to prevent premature payload release in normal tissues, reducing systemic toxicity
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long R3) is a modified analog of naturally occurring IGF-1
Wegovy was developed for weight management, where clinical trials showed that higher doses (up to 2.4 mg) worked better for appetite suppression and weight loss
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