Clinical evidence SELECT cardiovascular outcomes SELECT enrolled 17,604 adults aged 45 years with established atherosclerotic cardiovascular disease (prior MI, stroke, or symptomatic peripheral arterial disease) and BMI 27 kg/m, but without diabetes, randomizing them 1:1 to semaglutide 2.4 mg SC weekly (after titration) or placebo on top of standard CV therapies
Possible Adverse Reaction Semaglutide is generally well-tolerated, but some individuals may experience nausea, vomiting, constipation, and digestive discomfort
Recent studies have shown trizepatide tends to trigger the largest weight loss
During this stage, the medication helps support stability instead of continuing active weight loss
To build treatment plans, our clinicians use a metabolic health assessment called MetabolicPrint that uncovers the root causes of weight challenges to create a foundation for a personalized treatment plan