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However, the trajectory is clear

Although the etiology of depression has not been fully elucidated, current scientific data emphasize the role of neurotrophic factors deficiencies, disturbed homeostasis between the nervous system and the immune and endocrine systems, as well as disturbances in brain energy metabolism and dysfunctions in the gut-brain axis as important factors in the pathogenesis of this neuropsychiatric disorder

This lack of protein ends up leading to less collagen and elastin being produced in the skin. These medications also tend to cause loss of bone density as well as muscle mass, he adds

It is the most bioavailable form of B12, and also the most active, working mostly in our brains, nervous system, and liver (Lindstrand, 1964)

211 Electrolytes and energy metabolism Electrolytes such as potassium (K + ), calcium (Ca 2+ ), and magnesium (Mg 2+ ) play crucial roles in modulating various metabolic pathways and enzyme activities, thereby regulating cellular energy metabolism