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In evoke and evoke+, mean changes in clinical dementia rating sum of boxes score from baseline to week 104 were 2.3 (SE 0.1) and 2.2 (0.1) with semaglutide, compared with 2.3 (0.1) and 2.1 (0.1) with placebo (estimated difference 0.08, 95% confidence interval 0.35 to 0.20, P=0.57 in evoke and 0.10, 0.17 to 0.38, P=0.46 in evoke+)

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The findings were then combined, and meta-analyses were performed to examine and interpret the results

AOD 9604 is a synthetic peptide fragment derived from the C-terminus of human growth hormone (hGH), specifically amino acids 176191

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