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Wollenhaupt-Aguiar B, Kapczinski F, Pfaffenseller B

For patients suffering from the painful tingling, numbness, and burning sensations of peripheral neuropathy, B12 supplementation may offer a physiological pathway to relief and holds promise for supporting the autonomic and peripheral nervous systems in complex post-viral syndromes

At the level of adipose tissue, GIPR activation promotes fatty acid uptake during energy surplus and fatty acid release during energy deficit, effects that complement the appetite suppression driven by GLP-1R

It is "metabolically expensive." It burns through energy faster than the average brain because it is hyper-sensitive to sensory input (light, sound, smell, barometric pressure)

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