In their meta-analysis combining the results of twelve randomized controlled trials, Veronese and colleagues reported a significant decrease in depression severity after acetylcarnitine supplementation as monotherapy compared with placebo intake or no intervention [143]
Additional sources: Supplier data (purity 99%, blend ratio 1:1, research-only status)
The molecule is small, cheap to synthesise, and would be difficult to defend commercially
Each compound adds dose changes, timing, storage, measurement needs, and possible adverse effects
There are also several types of hyperpigmentation, such as melasma, post-inflammatory hyperpigmentation, and age spots