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As noted, semaglutide often leads to harder stools or less frequent bowel movements because the gut is moving slower and perhaps absorbing more water from stool
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a) activation of the substrates
Leukemia 25 , 960967 (2011)
Given the pronounced effect of tau elimination observed in in vitro and in vivo studies, selecting patients who test positive for tau biomarkers (CSF, blood, or positron emission tomography) could enhance the likelihood of achieving significant disease modification
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