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Tissue concentrations reach 10 to 20 times the levels achieved by serums
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Runners with this condition typically experience pain directly at the back of the heel, often accompanied by bony prominence or calcification
The compound is typically stable under physiological conditions and can be administered topically or systemically, depending on the intended use
394 Similarly, a pH-responsive niosomal platform codelivering doxorubicin and curcumin achieved enhanced cytotoxicity via tumor-selective drug release and synergistic activity, underscoring the value of smart codelivery systems in overcoming chemoresistance
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