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Through co-immunoprecipitation (CO-IP) experiments, we discovered that FOXO4-DRI prevents the binding of FOXO4 to P53, facilitating the phosphorylated P53 nuclear exclusion, which subsequently trigger BAX and cleaved caspase-3, leading to the apoptosis of senescent cells
doi: 10.13344/j.microbiol.China.230433 44 HuangB.WangH.LiuS.HaoM.LuoD.ZhouY.et al
Lyophilized: 12-24 months
The results showed that specific signaling molecules, such as the protein kinase Akt, were fully activated by c-Met and other signaling receptors cooperators
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