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While there are many antioxidant compounds in our diet, GSH (the form that we normally call l-glutathione is the reduced form of GSH) is the only antioxidant that is produced in all of our cells for the purpose of protecting us from oxidants and other toxic challenges

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Common causes of histamine intolerance include: Impaired DAO (diamine oxidase) activity , the enzyme responsible for breaking down histamine in the gut Gut inflammation or leaky gut , which increases histamine absorption Dysbiosis , particularly bacteria that produce histamine Nutrient deficiencies , especially vitamin B6, zinc, and copper imbalance Chronic stress and cortisol dysregulation Estrogen dominance , which slows histamine clearance Environmental triggers , including mold, chemicals, and allergens Many patients labeled with histamine intolerance are actually experiencing histamine overproduction combined with impaired clearance , which requires a broader clinical approach

Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer