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This depends on the individual pain tolerance, needle size, injection technique, and injection site

For example, someone with severe B12 deficiency and neurological symptoms might need more frequent injections at first

And since having too much B12 isnt harmful (the body simply excretes the excess), its easier and cheaper to just get a shot (B12 injectables cost $14 apiece if bought online or $20 to $70 at a spa or doctors office)

However, full benefits typically emerge over 2-4 weeks as your body's B12 stores replenish

Methylated B12 refers to a form of vitamin B12 that has been chemically altered to include a methyl group, making it more readily absorbed and utilized by the body, especially for those with certain genetic mutations affecting B12 metabolism