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Further studies indicated that HO-1 induced ferroptosis by inhibiting GPX4 expression (97)
By contrast, original SC- cells were labeled GCG + , INS-GFP , NKX6.1 , and mCherry , whereas SC- cells transdifferentiated from SC- cells were labeled GCG + , INS-GFP, NKX6.1 , and mCherry + , indicating inheritance of mCherry from SC- cells despite loss of the -cell identity marker NKX6.1 (Supplementary information, Fig
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& Kastin A.J
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