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Gheita, Tamer Atef et al
By rule, a Direct to Phase II topic will not fund a feasibility study, because feasibility is already supposed to exist
Although the relevance of these mechanisms in MMNST remains to be fully elucidated, we hypothesize that, in this case, anlotinib contributed to durable disease control not only through its established antiangiogenic and antiproliferative actions but also by promoting vascular normalization, reshaping the immune microenvironment, and potentially modulating the PRKAR1A/ERK axis
Methods 14 , 607614 (2017)
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