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The combination produces additive effects through dual receptor engagement

Using degraded or partially compromised peptide material can produce confounding data that is difficult to interpret and potentially impossible to replicate

Finally, we identify current research gaps and propose future directions toward harnessing AST for promoting cognitive resilience and delaying the progression of neurodegenerative disorders

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These features make SLU-PP-332 a valuable chemical probe for dissecting ERR-dependent physiology in cells and intact animals