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HIV-1 Tat promotes lysosomal exocytosis in astrocytes and contributes to astrocyte-mediated tat neurotoxicity
(PubMed) Zuo H, Svingen GFT, Tell GS, et al
Reproducibility Experimental reproducibility also depends on consistent manufacturing practices and standardized laboratory procedures
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184,185,199 Rational combinations, such as PARPis plus ATR or WEE1 inhibitors, aim to exacerbate replication stress and collapse replication fork stability, particularly in tumors with partial or context-specific DDR competence
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