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If theyve already been on a GLP-1 medication and their body is adapted to the drug class, their provider might move through the early dose escalation steps more quickly

[1] In clinical practice the transdermal estradiol system is most often prescribed for the treatment of moderate to severe vasomotor symptoms such as hot flashes and night sweats, for the prevention of postmenopausal osteoporosis in women at significant fracture risk who cannot tolerate or have contraindications to alternative therapies, and as replacement therapy in individuals with primary ovarian insufficiency or oophorectomy where endogenous estrogen is deficient

For patients with PCOS, long-term use of metformin may cause adverse reactions, and its safety still needs to be further evaluated

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One of the trials in the program followed patients who stopped taking semaglutide after a period of treatment