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The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease [PMID: 11735244] Laboratory literature summary: The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats
The medication enhances the effectiveness of lifestyle interventions rather than replacing them
IGF-1 has a molecular structure similar to insulin and possess cross-receptor to activate the downstream pathway, and IGF-1 can also bind IR and specifically activate insulin receptor substrate (IRS), a downstream insulin receptor substrate [24, 25]
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