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Rushing this process doubles the risk of severe gastrointestinal symptoms and increases the odds of early discontinuation

If they worsen or begin interfering with daily activities, that warrants a conversation about dose adjustment

Injectable research studies have similarly reported low rates of adverse events, though this should not be read as a clinical endorsement for any particular use

Whilst day-to-day hypoglycaemia was not coded in our network, we employed hypoglycaemia requiring hospital admission as a surrogate outcome of severe hypoglycaemia and there was no difference in the incidence in our cohort compared to the general population with type 1 diabetes

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