The working hypothesis in the scientific community is that GHK, by delivering copper and interacting with cellular signaling nodes, helps restore a more "youthful" transcriptional signature
SIRT1 activation restores autophagy by deacetylating FOXO3a and upregulating autophagy-related genes, including Atg5 and LC3-II, enhancing cellular stress adaptability and improving insulin sensitivity

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It appeared to decrease the chromosomal aberrations in the bone marrow by 23% and improve the life span by 24% compared to the control group