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In the context of the brain, oral infection with F.n in AD models induces gut dysbiosis, systemic inflammation, and neuropathology, including increased A142 and p-Tau expression, without direct brain detection, implicating the gut-brain axis (Yan et al., 2022
Gentiana Scabra root extracts induce GLP-1 secretion in human cells via a G-protein subunit-mediated route, resulting in the release of GLP-1 and insulin, which mitigate hyperglycemic condition in a type 2 diabetes mice model
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The capsule shells are made up of gelatin
Additionally, GLP-1 RAs inhibit the NF-B pathway, which is central to the regulation of inflammatory responses (102, 103)
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