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If your B12 levels are already normal, injections are unlikely to make a meaningful difference
Glycolate, produced from glyoxylate in the mitochondria of non-hepatic tissues via the activity of the HAO1 encoded enzyme, can delivered to the blood and transferred to the liver where it can be used for glycine synthesis in the peroxisomes
Stanford, K
Once it is maxed out, anything left over has to rely on the second pathway, passive diffusion, where B12 simply seeps across the intestinal wall on its own
This stops deficiency from coming back
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