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1,2 Although the clinical diagnosis of PD relies on the appearance of motor manifestations, extensive neuropathological dissemination initiates decades earlier, posing a significant challenge for early diagnosis
10.1016/j.tem.2003.12.002 Trends Endocrinol
Fuino L, Bali P, Wittmann S, Donapaty S, Guo F, Yamaguchi H, Wang HG, Atadja P, Bhalla K
ACC is a vital enzyme in fatty acid synthesis that can catalyze the carboxylation of acetyl-CoA to malonyl-CoA [17]
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During a 12-month follow-up, 10 out of 12 patients maintained normal intestinal permeability and did not experience disease relapse
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