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It has been widely reported that a reduction of AKT phosphorylation leads to FOXO3a activation and increased MAFbx and MuRF1 transcription, thus controlling cell survival and cell proliferation
The viral RNA is then transferred into the CD4+ T cells (Figure 1)
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Altogether, this dataset suggests that prolonged, but not acute, activation of GLP-1R induces metabolic reprogramming leading to increased glycolysis and cellular hypertrophy in BRIN-BD11 cells
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