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Bariatric surgery continues to stand apart as a well-established, insurable, and durable treatment for obesity in California

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The weekly injections produce greater average weight loss, and branded Saxenda has had long-term supply problems in the UK

ZEP-0002-VL-IFU-20260422 This Instructions for Use has been approved by the U.S

Beyond that: Consider Tirzepatide If: You want an FDA-approved, commercially available medication You have type 2 diabetes (Mounjaro is specifically approved for this) You prefer a medication with more long-term safety data Your insurance covers tirzepatide You need predictable access to medication supply Consider Waiting for Retatrutide If: You've plateaued on other GLP-1 medications You're interested in the potential metabolic benefits of glucagon activation You're comfortable waiting for FDA approval (expected 2027) You want potentially greater fat loss based on early trial data Switching From Tirzepatide to Retatrutide No established dose conversion exists