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Semaglutide targets one specific hormone pathway, while tirzepatide is a dual-action drug targeting both GLP-1 and GIP receptors
This point is relevant since acute pancreatitis is an unpredictable and potentially life-threatening disease.7,8 Previous systematic reviews have explored the risk of acute pancreatitis with these drugs.911 However, these studies have evaluated different GLP-1RAs, involved comparisons between different hypoglycaemic drugs without including a placebo arm, did not analyse the different administration regimens of semaglutide, or failed to include the latest published studies
There are several limitations in the current study
You might have heard other brand names like Wegovy and Rybelsus
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