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In Keap1 knockdown ( Keap1 KD ) mice, the Keap1 mRNA level is reduced to approximately 5% of that in wild-type mice, and constitutive Nrf2 activation is observed in various tissues, such as liver, lung, and kidney

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Ginsenoside Rh2-O suppresses hepatocellular carcinoma by inducing cell cycle arrest and apoptosis via activation of both intrinsic and extrinsic pathways