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Kennedy Medical Center, Edison, New Jersey with non-lacunar ischemic infarcts
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Fer-1 has also been found to inhibit ROS/RNS, attenuating rotenone-induced -synuclein aggregation in dopaminergic SH-SY5Y cells (Kabiraj et al., 2015), thereby reversing MPTP-triggered behavioral deficits in a mouse model of PD and protecting the neurons ( 3.2 Alzheimers disease Alzheimers disease (AD) is marked by the gradual deterioration of neurons within the CNS
Many studies had small sample sizes, and trial quality varied
Lithium protects against oxidative stress-mediated cell death in -synuclein-overexpressing in vitro and in vivo models of parkinsons disease
