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Another important dopaminergic population of neurons in the midbrain arises from the substantia nigra and projects to the dorsal striatum (the nigrostriatal pathway)
no extra precautions are needed
( G X ) BP measurements before (control) or after ( G I ) induction of hypertension with 2 weeks of access to L-NAME in drinking water and ( J L ) acute semaglutide treatment in L-NAME-induced hypertensive mice ( n = 1718), ( M O ) induction of hypertension 3 weeks after AAV8- Ren1d viral transfection ( n = 57) and ( P R ) acute semaglutide treatment in AAV8-Ren1d-induced hypertensive mice ( n = 8-13), and ( S U ) induction of hypertension 3 weeks after Ang II minipump implantation ( n = 3-7) and ( V X ) acute semaglutide treatment in Ang IIinduced hypertensive mice ( n = 6-7)