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Some patients notice stronger appetite suppression in the afternoon following a morning injection, while others experience more stable satiety when dosed in the evening before a lighter next-day appetite
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The body may no longer be used to it
[1] [2] The pivotal clinical trials evaluating tirzepatide for type 2 diabetes (SURPASS programme) and obesity (SURMOUNT programme) did not identify hot flushes as a significant treatment-emergent adverse event
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