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Recall that the 16-OH-E1 estrogen metabolites are proliferative (cause tissue growth), thus, anecdotally we see elevated 16-OH-E1 levels associated with proliferative conditions such as heavy bleeding, breast tenderness, endometriosis, and fibroids
Furthermore, SAMe is a cornerstone therapy for various hepatic conditions
For type 2 diabetes management (as opposed to weight loss alone), semaglutide is also marketed as Ozempic at a maximum dose of 2.0 mg weekly
For any immediate trouble breathing or swelling of the lips/tongue, call 911 or go to the nearest ER right away
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