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Nearly all participants lost at least 5% of their body weight, and roughly 60% reached their weight loss target of 20% or more

At the heart of the complaint are comments made by Martin Holst Lange, formerly the company's head of development and now its chief scientific officer, who is accused of concealing that the dosing regimen in REDEFINE-1 was flexible, allowing patients to modify their dose of CagriSema throughout the trial to limit side effects, which meant that just 57% of them received the highest dose of the drug

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This piece is an attempt to fill that gap, sourced from peer-reviewed literature rather than marketing copy