Additionally, BCL2-inhibitors have been shown to have senolytic effects in some senescent cell models 1,4
For lupus patients, this connection carries particular significance
What we prioritize first Before focusing on GLP-1 dosing terminology, we prioritize the clinical fundamentals that have the strongest relevance to cognitive longevity: blood pressure optimization ApoB, LDL, triglyceride, and lipoprotein(a) risk assessment insulin resistance and glucose-pattern evaluation visceral fat and body-composition measurement resistance training and aerobic fitness sleep quality and sleep apnea evaluation when appropriate hearing and vision support nutrition quality and protein adequacy alcohol moderation inflammation and immune-metabolic context hormone evaluation when clinically indicated social connection, cognitive engagement, and meaningful activity None of these interventions is glamorous by itself
Electrolytes = minerals (like sodium, potassium, magnesium ) that help with fluid balance and muscle/nerve function
Patients can't get their medicines, and we get a lot of phone calls, so it's a lot of extra work, and the patients have to call around to pharmacies to look and see where there is a supply." Shulman says there are several factors contributing to the shortages, including record-high prescriptions for the drug following the COVID-19 lockdowns, a surge in recreational use of the stimulant, and manufacturing limits put in place by the federal government