Contraindications encompass known hypersensitivity, insulinoma, and relative caution in preexisting hypokalemia
In some particular embodiments of the present invention, the coupling in the fragmental synthesis of the Lys 26 side chain in the preparation method is performed by condensing with DIC+A or B+A+C until the resin is detected to be transparent with ninhydrin, wherein A is chosen from HOBt or HOAt, B is chosen from HBTU, HATU, TBTU, PyAOP, or PyBOP, C is chosen from DIPEA or TMP
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