changing from tirzepatide to semaglutide For the first time, and were put in the same trial. SURMOUNT-5. Phase 3b RCT. 751 adults with obesity, no diabetes. 72 weeks. Both drugs at maximum tolerated dose. The Switching From Semaglutide to Tirzepatide

Among users of both semaglutide and tirzepatide, the study details that 36.9% reported nausea, 16.7% fatigue, 16.3% vomiting, 15.3% constipation, and 12.6% diarrhea

Curious about starting GLP-1s or want to know what to expect in your own first month

Never apply both in the same routine

Some studies have reported that depression caused by chronic stress disrupts the BDNFtropomyosin related kinase B (TrkB) receptor signaling pathway in the PFC and hippocampus, and ultimately contributes to impaired synaptic maturation, synaptic protein synthesis, and glutamate receptor cycling (Collingridge et al., 2010

How do GLP-1 drugs reduce inflammation