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Recommendations for selenium intake Although we lack evidence that selenium supplementation results in clinical improvement in autoimmune thyroiditis (other than in mild Graves orbitopathy), it still makes sense to ensure that selenium intake is adequate, given the roles played by selenoproteins in human health ( Reference Rayman 100 ) and particularly in the thyroid ( Reference Schomburg 70 , Reference Schomburg and Kohrle 71 )

Lifestyle Factors: Factors such as diet, stress levels, and physical activity can impact glutathione levels and requirements