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To date, dulaglutide, semaglutide, and tirzepatide have been the three predominant GLP-1 therapeutics employed in the treatment of T2DM, and their applications have been broadened to include weight management
We show sulindac enriched oxidative phosphorylation in multiple myeloid and tumor cell clusters from obese mice, yet suppresses oxidative phosphorylation in the transcriptomic profiles of whole tumors from obese, this apparent contradiction may reflect altered cellular activation states or composition of tumors between groups, or context specific effects of the cell lines used
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doi: Davies, M., Pieber, T
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