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Analytical biochemistry 280 , 8086, doi: 10.1006/abio.2000.4498 (2000)
These receptors are coupled to inhibitory G-proteins (G i/o ), which inhibit adenylyl cyclase, deplete cyclic AMP (cAMP) levels, and suppress neuronal firing by opening potassium channels
When cytoplasmic concentrations of neurotransmitters rise dangerously high, TAAR1 activates G-protein-dependent signaling pathways that recruit intracellular kinases, including protein kinase C (PKC) and calcium/calmodulin-dependent protein kinase II (CaMKII) (Underhill et al., 2020)
For both goals: use both peptides in a combined protocol
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