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In the TRIUMPH-1 Phase 3 trial, participants on the highest dose of retatrutide lost an average of 28.3% of their body weight at 80 weeks

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In addition, other studies have shown that CoQ 10 H 2 content in adipose tissue gradually decreased with the development of obesity in both mice and humans, and that CoQ 10 H 2 synthesis-related enzymes were upregulated as a compensatory measure 43

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The fat needs to reach the mitochondria, where actual oxidation takes place, in order for the body to turn it into energy