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Over-the-counter oral homeopathic medications, herbal remedies, and nutritional supplements are acceptable
Starting treatment is a decision made between you and your doctor
For patients without diabetes using Wegovy for weight management: Routine blood glucose monitoring is not typically required , as hypoglycaemia risk is low Patients should be counselled about maintaining adequate nutritional intake despite appetite suppression Report any symptoms suggestive of hypoglycaemia (tremor, sweating, confusion) to their healthcare provider Annual HbA1c testing may be appropriate for those with prediabetes or metabolic syndrome For patients with type 2 diabetes on combination therapy: Self-monitoring of blood glucose (SMBG) frequency should be individualised based on hypoglycaemia risk Those on insulin or sulphonylureas should monitor more frequently, particularly during Wegovy initiation and dose escalation Continuous glucose monitoring (CGM) may be considered for high-risk individuals or those with impaired awareness, in line with NICE and NHS England access criteria Medication review and adjustment sulphonylurea and insulin doses often require reduction when starting GLP-1 therapy
These markers cover the treatable drivers of diffuse shedding, and they are most useful read together rather than one at a time
Gut microbiome modulation : Early research suggests that GLP-1 receptor agonists like semaglutide may influence gut microbiota composition, though the clinical significance remains unclear and evidence is limited
