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In a single piece, he concisely captures: the state of the field the most important clinical trials where the pipeline is headed These Clinical trials are raising the bar and expanding future treatment options: Retatrutide ~24% weight loss (triple agonist) MariTide 1216% weight loss (GLP-1 + GIP antagonist) CagriSema up to 20% weight loss + ~2% HbA1c drop Orforglipron oral GLP-1, HbA1c 1.5%, weight 7.6% IcoSema weekly semaglutide + once-weekly insulin Even more exciting
The main difference is that a prescription GLP-1 mimics the GLP-1 hormone and is crafted with a medical-grade formula
Nutrients 14 , 3525 (2022)
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Insulin and IGF-1 play integral roles in our metabolism and physiological development (tissue growth)
