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None of the compounds described is approved for human self-administration outside of properly regulated clinical trials

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JAMA Dermatol 157:10781088 Surboyo MDC, Santosh ABR, Hariyani N, Ernawati DS, Cecilia PH (2021) Clinical utility of dermoscopy on diagnosing pigmented papillary fungiform papillae of the tongue: a systematic review

After 10 days: about 25% remains

In cellular experiments, data are expressed as means SD