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This overactivation causes an influx of calcium ions into neurons, which, in turn, activates calcium-dependent enzymes, such as calpain, nitric oxide synthase and phosphatase, resulting in the degradation of cytoskeletal proteins and damage to cell membranes
Once a vial has been punctured, it should be discarded after 28 days even if liquid remains, since preservative effectiveness gradually decreases with repeated punctures and air exposure
The upper cervical spine contains and processes information about your position in space and communicates this information to your eyes and inner ears via nerves
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Roberts, M., Kumar, P., & Anderson, S
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